John Goodman

Fat Freddy Freekowtski (voice)

Woody Harrelson

Freewheelin' Franklin Freek (voice)

Pete Davidson

Phineas T. Phreakers (voice)

Tiffany Haddish

Kitty (voice)

Adam Devine

La La Anthony

Liza del Mundo

Phil LaMarr

Gilbert Shelton

Characters