Panos started working in the cinema and television business in the '80s. He had been an active member of the State Council of Cinematography under the authority of the Greek Ministry of Culture. He has participated in EAVE/Media Programme 1992 seminars for European producers. Panos is a member of the European Film Academy, President of S.A.P.O.E. (Audiovisual Producers' Association of Greece), founding member of the Hellenic Film Academy and member of the Academy's first Board of Directors.

He has produced over than 50 feature films that won national recognition along with commercial success. Among these are FROM THE SNOW by Sotiris Goritsas- 1993 (Cannes Quinzaine des Réalisateurs, Golden Alexander in the Thessaloniki Film Festival), END OF AN ERA by Antonis Kokkinos-1994 (Berlin FF), THE COW'S ORGASM by Olga Malea- 1997, EXTENDED PLAY by Yannis Xanthopoulos- 2006 (380.000 domestic box office), STRAIGHT STORY by Vladimiros Kyriakidis and Efi Mouriki- 2006 (400.000 domestic box office), SOUL KICKING by Yannis Economides- 2006 (Cannes- Semaine Internationale de la Critique 2006), IN THE WOODS by Angelos Frantzis- 2010 (premiere in Rotterdam Film Festival), KNIFER by Yannis Economides- 2010 (premiere in Busan Film Festival, 7 awards by the Hellenic Film Academy), STRATOS-TO MIKRO PSARI by Yannis Economides- 2014 (Berlinale Competition 2014), ROZA OF SMYRNA by Yorgos Kordellas- 2016 (360.000 domestic box office), BALLAD FOR A PIERCED HEART by Yannis Economides, SIEGE ON LIPERTI STREET by Stavros Pamballis , ARMY BABY by Yorgos Kordellas and PELE'S TEAM by Marios Karamanis, which is currently in production. Panos has also produced documentaries, shorts and TV series. His productions have participated in many International Festivals such as Cannes, Berlin, Carlovy Vary, London, Toronto, Istanbul and many others.

Over the years, Panos has worked on many international co-productions (with France, Germany, Canada, Turkey, Bulgaria, Hungary, Belgium and Cyprus).