Wayne Lytle was a long time musician, pianist and a drummer. He performed in and composed most of the music for progressive rock bands throughout high school, and later studied classical piano.

He first envisioned his idea of animated music in 1982, while an undergraduate student in music and computer science. In 1988, he joined the Cornell Theory Center, where he could experiment with his idea as a scientific visualization producer. He specialized in composing and later created all the music for Animusic.

He started experimenting with music visualization in 1990, when he created More Bells and Whistles at Cornell University. One year later, Lytle received an award from IBM for his work in computer animated music. Lytle founded Animusic (originally under the name Visual Music) in 1995 with his associate David Crognale That same year, Animusic created Beyond the Walls. A few years later, they released Animusic 1 originally in 2001 (and re-released in 2004) and Animusic 2 in 2005. Animusic is making another musical film called Animusic 3 and hoped to release it in October 2013, but the release date has been postponed and is currently uncertain.

The future of Animusic 3 is uncertain. Crognale left the company and Lytle has RSI (repetitive strain injury). However, Wayne works with his family to finish the third installment.

He now lives in New York State with his wife Patricia and he has two children named Andrew and Elizabeth Lytle.