Jack O'Brien (born June 18, 1939) is an American director, producer, writer and lyricist. He has won three Tony Awards and been nominated for seven more, and won five Drama Desk Awards.

O'Brien has directed and produced musicals, including The Full Monty and Hairspray, contemporary dramas such as The Piano Lesson, The Invention of Love and The Coast of Utopia, Shakespeare classics, including Hamlet and Henry IV (a combination of Part 1 and Part 2), and operas, including Il trittico at the Metropolitan Opera.

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