Self-taught animator and builder, Bruno Isaac Grade Caetano graduated from the Center for Multimedia Studies and Research at the Faculty of Fine Arts of Lisbon with a specialization in Stop Motion. Despite having a strong preference for this technique, his professional career led him to participate in several projects in the most varied of animation techniques as well as other areas of artistic interest. He has worked as an animator, producer and director at several production companies. Bruno Caetano is a founding member of COLA Animation, an ever growing international cooperative of united artists, focused on producing, teaching and promoting animation worldwide.

When it comes to his work as a producer, Bruno Caetano has achieved some of the highest nominations and distinctions possible. With an already vast catalog of auteur films with the COLA Animation seal, from talented directors from around the world, some of these films were selected and awarded at festivals such as Cannes, Toronto International Film Festival, Melbourne International Film Festival, Locarno Film Festival, Annecy, Zagreb Animation Festival, among other renown festivals. In 2022/2023, with "Ice Merchants" by João Gonzalez, he was the first Portuguese animation producer to be nominated for a European Film Award, the second Portuguese animation producer to receive the Annie Award for best short film and, in January 2023, he became the first Portuguese producer to be nominated for an Academy award, the coveted Oscar, of which, since 2023, he is now a member.