Ryle Santiago is an actor, singer, dancer, content creator, and brand ambassador. He comes from a showbiz family being the son of actress, Sherilyn Reyes-Tan, and ABS-CBN executive, Reily “Junjun” Santiago. His paternal grandparents were director, Pablo Santiago, and actress, Cielito Legaspi.

Ryle made his acting debut in the musical drama "Bakwit Boys" (2018). His is known as a member of the Filipino boy group #Hashtags from the noontime show "It’s Showtime." On March 31, 2023, he signed a contract with Viva Artist Agency.

Ryle also goes by the name Ryle Paolo Tan, using his stepfather's last name, after his mother's remarriage.