Amy Rose Locane (born December 19, 1971) is an American convicted felon and former actress. She is best known for her role in John Waters' 1990 musical comedy Cry-Baby.

In 2013, Locane was convicted of vehicular homicide and assault by auto after causing the death of a 60-year-old woman in a 2010 drunk driving crash. She was driving with a blood-alcohol level three times the legal limit at the time. Locane spent nearly 8 years in prison for the crime, split between two sentences.