Mei is the second of three daughters. Her parents, who love anime, named her after Mei Kusakabe from the film, "My Neighbor Totoro".

Mei debuted as an idol in 2014 with the military-themed unit "Tenkou Shoujo Kagekidan" (later renamed "Tenko Shojo*"). She announced her graduation from the group on September 10, 2019.

Beginning in September 2016, Mei has hosted readings of original essays, short stories, and scripts entitled "Mei Nadeshiko" (夢詠撫子).