Brian H. Hook (born 1968) is an American diplomat, lawyer and government official. In 2021, he joined Cerberus Capital Management as vice chairman for global investments. He is an adjunct professor at Duke University’s Sanford School of Public Policy.

He served as U.S. Special Representative for Iran and Senior Policy Advisor to Secretary of State Mike Pompeo from September 2018 to August 2020. He was the Director of Policy Planning under Secretary of State Rex Tillerson.