In Tokyo, a weak, unassertive boy named Sena Kobayakawa enters the high school of his choice, Deimon Private Senior High School. Sena's only remarkable physical abilities are his running speed and agility, which are noted by the school's American football team captain Yoichi Hiruma. Hiruma forces Sena to join the Deimon Devil Bats football team as its running back. To protect his identity from other teams who want to recruit him, Sena is forced to publicly assume the role of the team secretary and enter the field under the pseudonym of "Eyeshield 21" wearing a helmet with an eyeshield to hide his features.
Hiroshi Shimozaki
Naosumi Kadoguchi
Kouichi Nagano
Satoshi Muro
Miyu Irino
Sena Kobayakawa / Eyeshield 21 (voice)
Atsushi Tamura
Yoichi Hiruma
Aya Hirano
Mamori Anezaki
Mamoru Miyano
Haruto Sakuraba
Kappei Yamaguchi
Raimon Tarou
Daisuke Hirakawa
Hayato Akaba
Daisuke Ono
Kengo Mizumachi
Gifted with speed and agility, a bullied teen aims to reinvent himself by joining his high school's undermanned American football team.
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