Sandra Uusberg (neé Üksküla; born April 24, 1986) is an Estonian actress.

She graduated from Vanalinna College of Education (piano specialty in 2000 and theater school in 2005) and in 2010 from the Estonian Academy of Music and Theater School of Performing Arts (XXIV flight) majoring in acting. She has been working at the Tallinn City Theater since 2010.

Sandra Uusberg is the granddaughter of Aarne and Siina Üksküla and the sister of Kristjan Üksküla. She is married to actor and director Uku Uusberg; they have a son born in November 2014 and a daughter born in April 2016