Antonio Isasi-Isasmendi Lasa (22 March 1927 – 28 September 2017) was a Spanish film director and producer.

Isasi-Isasmendi began working in the production firm Emisora Films as an assistant manager, film editor, scriptwriter, lead producer, and finally director. In 1955 he founded his own production company, Producciones Isasi in Barcelona. He founded a second firm, Moon Films, in Madrid.

In the mid-1960s he directed a series of action films designed for the wider European market including Scaramouche (The Adventures of Scaramouche) in 1963 and Estambul 65 (That Man in Istanbul) in 1965. He made some English-language films, most notably They Came to Rob Las Vegas. He abandoned directing for a decade after making El Perro (The Dog) in 1977 in favour of producing and distributing films before returning to the director's chair with El Aire de un Crimen (The Hint of a Crime) in 1987.